Professor Dan Xie has a strong educational background of bioengineering and genetics. He has a long history of researching in the fields of gene regulation network, liquid biopsy and single-cell sequencing. He developed new experimental methods and machine learning algorithms to analyze the high-throughput multi-omics sequencing data including genome, transcriptome, DNA epigenome, cell-free DNA epigenetic modification. He has made a series of important scientific findings with biological significance, including the discovery of dynamic trans-acting factor colocalization network in human cells, longitudinal personal DNA methylome dynamics in a human with a chronic condition, improved Macaca fascicularis gene annotation, and the establishment of open chromatin landscape in non-small cell lung cancer.
He has authored numerous highly-cited publications on influential journals, including Cell, Nature Biotechnology, Nature Medicine, Cell Research, Genome Research and Cancer Research.
University of Science and Technology of China (USTC), B.S., 2003 University of Science and Technology of China (USTC), M.S., 2006 University of Illinois at Urbana-Champaign, Ph.D., 2011 Department of Genetics, Stanford University (Michael Snyder Lab), Postdoctoral fellow, 2011-2015 State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Professor, 2015 – present Center of Precision Medicine, West China Hospital, Sichuan University, Executive deputy director, 2015 – present
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